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Antibody-Drug Conjugate

NEXJENNER SERVICE

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Antibody-Drug Conjugate (ADC)

Development & Manufactureing

ADCs, biosynthetic fusion drugs combining antibodies and drugs via a suitable linker
are being developed as novel drugs with highly targeted therapeutic effects
and significantly reduced cytotoxic side effects.

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ADC Design and Development Support Services

Antibody selection

Target (bio)marker proposal

Design and fabrication of disease-specific linkers

Design and fabrication of disease-specific linkers

Drug selection

Proposal and selection of effective therapeutics including anticancer and autoimmune disease treatments

BGMP Sample Production

Small-scale production of drugs for nonclinical and clinical trials

ADC Analysis Services

Toxicity Review / Validation

Single and Repeated Dosage, Non-Target Toxicity, Immunogenicity

Chemical Analysis

DAR, Residual solvent, Free drug

Assay Validation

FPLC, LC/MS, ELISA

In vitro/in vivo Testing

Cytotoxicity Testing, Laboratory Animal Disease

Specificity Confirmation

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